A Look into High Resolution Melting Industry……Deep Analysis…..


Global High Resolution Melting (HRM) market  is expected to reach USD 131.7 billion by 2022 according to a new report by Grand View Research Inc.  Increasing incidences of cancer, sickle cell anemia, HIV and other STDs are expected to positively reinforce demand for smart and simple molecular diagnostics. According to the Genetic and Rare Diseases Center (GARD) in 2014, 10% of the U.S. population that is nearly 30 million people were suffering from genetic disorders. Some key disease statistics are reported below:
Biopharmaceutical innovators are at the forefront of the human response to the coronavirus pandemic. A significant number of major biotech firms are in the midst of a race to investigate the Sars-Cov-2 genome and prepare a viable vaccine for the same. As compared to the speed of response to SARS/MERs etc, the biotech entities are investigating SARs-Cov-2 at an unprecedented rate and a considerable amount of funds are being put into the R&D. With multiple candidates in trial, the public and private sectors are anticipated to work in unison for the foreseeable period, until a vaccine is developed for Covid-19. The report will account for Covid19 as a key market contributor.
As per the estimates provided by CDC, number of acute cases of hepatitis C reported in the United States increased from 1,778 to 2,138 from 2012 to2013. According to the UNAIDS report, out of the 36.9 million people that are suffering with HIV/AIDS, 17.1 million are unaware about disease occurrence due to unavailability of testing services
As per the WHO estimates in 2015, there are over 130-150 million people suffering with HCV globally
Based on analyzing the disease trends and relatively lower treatment rates suggests that the demand for gene mutation and other genomic tests are expected to increase significantly over the next few years. Recent developments in the field of QPCR, next generation sequencing, genomics and big data analytics have been instrumental in strengthening the precision medicine approach. The U.S. FDA has already approved some of the treatments which are designed to meet the requirements of a specific genetic makeup or the genomic profile of the patient’s tumor.
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For instance, the U.S FDA has approved a new treatment for cystic fibrosis (CF) in January, 2012. The drug kalydeco was approved for patients reported to have a specific genetic mutation known as “G551D mutation. The number of mutations which can lead to CF is in hundreds, and the G551D mutation is responsible for nearly 4% of the cases in the U.S.
Furthermore, in 2015, the Obama administration has announced the Precision Medicine Initiative with an investment of USD 216 million in the 2016 president's budget. This initiative is expected to positively reinforce the HRM analysis market over the forecast period.
Further key findings from the study suggest:
·         In 2014, North America dominated the overall HRM analysis market with a share of nearly 42%. Key factors attributed are high disease prevalence rates, presence of large number of academic universities; strong pharmaceutical and biotech industry, presence of large number genetic testing centers, and rapid adoption of novel technologies for improving the healthcare outcomes.
·         Asia pacific is identified as the fastest growing region over the forecast period. Key reasons attributed are increasing public and private expenditure on molecular diagnostics and genetic testing, increasing prevalence of genetic disorders, and increasing burden of chronic diseases such as cancer, COPD, HIV and others.
·         Key market players in the High Resolution Melting analysis market include, Roche Molecular Systems, Idaho Technology Corporation, Kapa Biosystems, Thermo Fisher Scientific, Premier Biosoft and Qiagen. Furthermore, Roche Molecular Systems leads the industry with the highest R&D expenditure and commands a significant market share. 
The global high resolution melting analysis market size was valued at USD 75.3 million in 2016 and is expected to grow at a CAGR of 9.8% during the forecast period. Increasing investment in R&D, growing applications of this technology in epigenetics, and mutation scanning are some of the factors propelling the market growth. Benefits such as no use of probes, closed tube system, prevention of post-PCR sample contamination, and high accuracy of melting profile analysis are driving the HRM analysis market growth. 
The market dynamics indicate that various players operating in this space compete, based on product specifications, such as reagents, software & instrument capabilities, and prices. The technology used to manufacture, quality of the product, and sample processing capacity are the key variables expected to impact the usage rates of these products. Increasing collaboration between government bodies and major players to introduce technologically advanced products and reduce overall healthcare costs is expected to further intensify the HRM analysis market competition.
Factors such as growing prevalence of chronic diseases, rising demand for personalized medicine and favorable government initiatives are expected to have a positive impact on the HRM analysis market. Personalized medicine, which is also known as precision medicine, is an innovative and powerful approach to prevent and treat the disease after considering the differences in different genetic combinations, lifestyle, and environmental factors.
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Grand View Research has segmented the High Resolution Melting analysis market on the basis of product, end-use, application: 
High Resolution Melting Analysis Market Product Outlook, by Revenue (USD Million, 2015 - 2022)
·         Instruments
·         Reagents
·         Software
High Resolution Melting Analysis Market End-Use Outlook, by Revenue (USD Million, 2015 - 2022)
·         Academic Researcher
·         Clinical Diagnostics
High Resolution Melting Analysis Market Application Outlook by Revenue (USD Million, 2015 - 2022)
·         Detection of Acquired Mutations/Mutation Scanning/SNP Typing
·         Microbial Species Identification
·         Zygosity testing
·         Epigenetics/ Methylation Profiling and drug-resistant
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.


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