A Look into Intravenous Immunoglobulin (IVIG) Industry……Deep Analysis…..
Global intravenous
immunoglobulin market is expected
to reach USD 10.9 billion by 2022,
according to a new study by Grand View Research, Inc.
Multiple therapeutic regimens are being
followed across the globe in attempts to come up with a reliable treatment for
Covid-19. One line of treatment includes the use of hydroxychloroquine, while a
second treatment line focuses to use antiviral drugs used in the disease
management of HIV. Both these approaches have surged demand from advanced
antivirals and antimalarial drugs. This impacts the drug manufacturers as an
off label indication for these drug classes has to be worked upon. At the
moment, the WHO has not prescribed any of these approaches, neither they have
commented if one is better than the other. The report will account for Covid19
as a key market contributor.
The increasing prevalence of
immunodeficiency diseases coupled with the adoption of IVIG therapies is
expected to fuel market growth over the forecast period. In addition,
increasing off-label use of immunoglobulin and investments in the healthcare
sector are factors propelling market growth. Moreover, increasing incidences of
bleeding disorders and rising geriatric population base are the factors
attributing towards the industry growth.
The rising incorporation of
subcutaneous immunoglobulin in the treatment of primary immunodeficiency
diseases and in replacement therapy is anticipated to provide growth platform
to the immunoglobulin market in the next seven years.
The global immunoglobulin industry is consolidated
in nature and a limited number of players have a high level of dominance over
the global revenue share. The key players are Biotest AG, Baxter
International Inc., Octapharma AG, LFB Biotechnologies, Grifols SA, CSL
Behring, China Biologics Products Inc., Kedrion Biopharma, and BDI Pharma Inc.
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The global intravenous immunoglobulin (IVIG) market size was
estimated at USD 9.09 billion in 2016 and is anticipated to grow at a CAGR of
7.1% over the forecast period. Growing geriatric population, rising prevalence
of immunodeficiency diseases, increasing adoption of IVIG treatments and rising
use of off-label indications are the key drivers of the market. Rising number
of patients with immunodeficiency disorders is the primary cause for the
development of IVIG preparations.
Further key findings from the study
suggest:
·
Increasing demand for immunoglobulin
replacement therapies to treat hypogammaglobulinemia diseases is driven by
rising awareness levels amongst patients and increasing incidences of the
disease. This has attributed towards hypogammaglobulinemia diseases segment’s
dominant market share in 2014
·
The U.S. National library of Medicine and
the National Institute of Health published a report, which states that in 2012,
about 6 million patients suffered from PID (Primary immunodeficiency Diseases)
globally and is expected to grow further, representing the potential growth for
the treatment of hypogammaglobulinemia in the coming years
·
The Kawasaki disease market segment is
expected to grow at a rapid pace with a lucrative CAGR of over 8.0% from 2015
to 2022 owing to the massive adoption of IVIG treatment in the aforementioned
disease management
·
Intravenous route of administration is most
commonly used in the treatment of autoimmune diseases and accounted for the
largest market share in 2014. Subcutaneous administration is anticipated to be
growing at a lucrative CAGR of over 9.0% during the forecast period. This can
be attributed to the associated potential advantages such as fewer side effects
and shorter response time with subcutaneous route of administration and rising
preference for subcutaneous home-based self-infusion
·
North America held the largest regional
market share in terms of revenue in 2014 due to the presence of a
well-regulated healthcare system, the larger pool of target population, and
high patient awareness pertinent to the plasma protein products
·
The European intravenous immunoglobulin market
is expected to show an impressive CAGR at above 6.0% over the forecast period
owing to the increasing number of patients with bleeding disorders and growing
number of CIDP patients
·
Countries such as India, China, and South
Africa are expected to show significant growth over the forecast period owing
to improving healthcare facilities, rising healthcare expenditure, and growing
public awareness of immune deficiency disorders
·
Chinese IVIG market is poised to show a
growth rate of over 7.0% owing to the presence of major market players such as
China Biologics Products, Inc. facilitating the industry growth
·
Some key players of IVIG industry are
Biotest AG, Octapharma AG, China Biologics Products Ltd., Baxter international,
Inc., CSL Limited, LFB group and Grifols S.A.
·
These key players are adopting strategic
alliances to sustain the competition. These initiatives include mergers &
acquisitions, collaborations, and new product developments.
·
For instance, in January 2016, Biotest AG
entered into a collaborative agreement with Kedrion Pharma to expand the
distribution capabilities of Bivigam. This was carried out to improve
production facility utilization and manage idle capacity costs enabling better
optimization.
According
to the W.H.O, currently, there are over 50 different Primary Immune Deficiency
(PID’s) such as specific antibody deficiency, X-lined hypo-gamma-globulinemia,
and others. PIDs include 176 different types of rare hereditary disorders.
According to the U.S. National Library of Medicine and National Institute of
Health, approximately 6 million patients are suffering from PID worldwide.
Growing incidences of these diseases is expected to boost the demand for
immunoglobulin therapies over the forecast period.
The
demand for IVIG therapies for the treatment of acquired and primary
immunodeficiency diseases is increasing as it is the most effective & the
only available treatment option. Moreover, sedentary lifestyle habits,
including consumption of saturated fats salt, & sugars, less physical
activities, and high alcohol consumption have led to the increase in the
prevalence of these diseases.Rising prevalence of lifestyle associated
disorders such as obesity & antibody deficiency disorders are the factors
expected to drive the growth.
Browse Press Release
of this report:
The
global geriatric population base is on a rise. According to a report published
by United States Census Bureau, the number of people aged 65 and older in the
U.S. was approximately 46.2 million in 2014 and is expected to reach over 98
million by 2060. Aging also weakens immune systems and consequently heightens a
patient’s susceptibility towards acquiring infectious diseases. The global base
of geriatric population is expected to grow over the next few years is expected
to serve this industry as a high impact rendering driver.
Grand View Research has segmented the global intravenous
immunoglobulin market on the basis of application and region:
Global Intravenous Immunoglobulin Market Application
Outlook (Revenue, USD Million, 2012 - 2022)
·
Hypogammaglobulinemia
·
CIPD
·
Immunodeficiency diseases
·
Congenital AIDS
·
Chronic Lymphocytic Leukemia
·
Myasthenia Gravis
·
Multifocal motor neuropathy
·
ITP
·
Kawasaki disease
·
Guillain-Barre syndrome
·
Others
Global Immunoglobulin Market Route of Administration
Outlook (Revenue, USD Million, 2012 - 2022)
·
Intravenous
·
Subcutaneous
About Grand View Research
Grand View Research, Inc. is a U.S.
based market research and consulting company, registered in the State of California
and headquartered in San Francisco. The company provides syndicated research
reports, customized research reports, and consulting services. To help clients
make informed business decisions, we offer market intelligence studies ensuring
relevant and fact-based research across a range of industries, from technology
to chemicals, materials and healthcare.
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