Demand for Pruritus Therapeutics and Impact of COVID-19……..


Global pruritus therapeutics market is expected to reach USD 16.38 Billion by 2025, according to a new study by Grand View Research, Inc. Growing worldwide prevalence of atopic dermatitis, allergic contact dermatitis and urticaria is expected to drive market growth during the forecast period. Introduction of new products based on scientific mechanistic understanding such as the identification of new T-cell subsets, particularly Th17, and Th22 and the patent expiration of PROTOPIC (tacrolimus) is expected to open up new avenues for manufacturers to capitalize on over the forecast period.
Multiple therapeutic regimens are being followed across the globe in attempts to come up with a reliable treatment for Covid-19. One line of treatment includes the use of hydroxychloroquine, while a second treatment line focuses to use antiviral drugs used in the disease management of HIV. Both these approaches have surged demand from advanced antivirals and antimalarial drugs. This impacts the drug manufacturers as an off label indication for these drug classes has to be worked upon. At the moment, the WHO has not prescribed any of these approaches, neither they have commented if one is better than the other. The report will account for Covid19 as a key market contributor.
Corticosteroids were the leading product segment in 2013 owing to high efficacy exhibited by this class of drugs in treating pruritic conditions by reducing inflammation and itching. Topical applications of corticosteroids have been found to be extremely effective in the treatment and maintenance therapies pertaining to pruritus.
Growing prevalence of conditions associated with pruritus such as atopic dermatitis, urticaria, and psoriasis is expected to serve the market as a high impact rendering drivers. Moreover, the presence of high unmet medical needs and the subsequent introduction of new products such as REMITECH capsules and Bilastine catering to these needs are expected to serve as future growth opportunities. 
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Further key findings from the study suggest:
·         Calcineurin inhibitor is identified as the most lucrative segment of the market on account of high usage rate of these drugs in combination therapy for the treatment of pruritus in patients suffering from chronic pruritus and growing market penetration rates. Moreover, the introduction of new products such as Pimecrolimus cream and Tacrolimus ointment is expected to further drive this market.
·         Anti-histamines owing to its growing use as a first line treatment and presence of drugs in pipeline with expected commercialization is also expected to grow at a healthy rate during the forecast period.
·         North America led the overall market in terms of revenue in 2013 majorly on account of the presence of high prevalence of diseases associated with pruritus, introduction of new products targeting the unmet medical needs and growing patient awareness levels.
·         The Asia Pacific pruritus therapeutics market is expected to grow at a CAGR of over 5.0% during the forecast period. Presence of high unmet healthcare needs and increasing prevalence of allergic contact dermatitis and urticaria in this region are some factors attributing to its rapid growth rate.
·         Some key participants of the pruritus therapeutics market include Sanofi, Pfizer, Tai Guk Pharmaceutical Company, Actavis, Trevi Therapeutics, Cara Therapeutics, Ocera Therapeutics Inc. and NeRRe Therapeutics.
·         Manufacturers adhere to rigorous R&D in an attempt to develop cost effective products and avoid barriers such as product recalls. In addition, this strategy is implemented keeping the unmet needs in consideration. For Instance, Creabilis has a molecule in the pipeline – CT327, which caters to the unmet needs associated with pruritus in patients suffering from psoriasis. 
Unmet needs available in the pruritus therapeutics market are analyzed by considering three attributes namely treatment rate, drug efficiency, and the currently existing gaps in therapeutic options. Treatment rate associated with pruritus is largely dependent upon the prevalence of diseases. Low prices and high willingness of patients are expected to further improve the treatment rates over the next six years. High opportunity segments such as the pruritus for psoriasis market are likely to encourage manufacturers to make modifications/additions to their existing product portfolio. Therefore, capitalization opportunity analyzed only on the basis of treatment rates is expected to remain at a moderate level over the next six years. The study analyzes all other attributes on similar grounds.
Corticosteroids, antihistamines, local anesthetics, counterirritants, immunosuppressant, calcineurin inhibitors and others are the key product segments analyzed in the scope of the study. Corticosteroids dominated the pruritus therapeutics market in 2013 with a revenue share of 23.7%. Corticosteroids are mostly used as the first line of treatment is also expected to contribute towards the aforementioned conclusion. Whereas, calcineurin inhibitors is expected to grow at the fastest CAGR during the forecast period owing to its high response rate and presence of strong pipeline of calcineurin inhibitors and semi-synthetic analogs of these inhibitors.
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Grand View Research has segmented the global pruritus therapeutics market on the basis of product, disease type and region:
Global Pruritus Therapeutics Product Outlook (Revenue, USD Million, 2012 - 2025)
·         Corticosteroids
·         Antihistamines
·         Local Anesthetics
·         Counterirritants
·         Immunosuppressant
·         Calcineurin Inhibitors
·         Others
Global Pruritus Therapeutics Disease Type Outlook (Revenue, USD Million, 2012 - 2025)
·         Atopic Dermatitis
·         Allergic Contact Dermatitis
·         Urticaria
·         Others
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.




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