How much will the ADME Toxicology Testing industry be worth in the Future????



The global ADME toxicology testing market size is expected to generate a revenue of USD 10.25 billion by 2025, according to a new report by Grand View Research, Inc., exhibiting a CAGR of 11.4% during the forecast period. Factors such as increased need to check late-stage drug failures with adoption of more appropriate toxicity testing methods by pharmaceutical companies is expected to aid revenue generation for the market.
Multiple therapeutic regimens are being followed across the globe in attempts to come up with a reliable treatment for Covid-19. One line of treatment includes the use of hydroxychloroquine, while a second treatment line focuses to use antiviral drugs used in the disease management of HIV. Both these approaches have surged demand from advanced antivirals and antimalarial drugs. This impacts the drug manufacturers as an off label indication for these drug classes has to be worked upon. At the moment, the WHO has not prescribed any of these approaches, neither they have commented if one is better than the other. The report will account for Covid19 as a key market contributor.
Absorption, distribution, metabolism, and excretion (ADME) toxicology testing is used to test toxic reactions caused by molecules in clinical trials on factors and systemic reactions such as chemical, pharmaceutical, and genetic. These toxicology testing procedures help in effective drug development, which limits or prevents toxic reactions to the body when administered. Toxicity levels are decided on the results of a series of tests conducted in near natural conditions, which represent almost real-time reactions between the drug and host.
As of 2017, approximately 43.0% of ADME toxicology testing areas carried out are based on cell culture tech. Cell culture technology is adopted widely owing to advantages such as near natural conditions and accurate results obtained at a cellular level.
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These assays are conducted for several types of toxic reactions or systems where toxic reactions might take place. Some of the toxicity tests are systemic toxicity, renal toxicity, hepatotoxicity, neurotoxicity, and other toxicities that might result in a living tissue. Advancements in testing methods are underway and this trend is likely to be picked up by many companies developing drug molecules. This will speed up the drug discovery process and boost market growth.
Further key findings from the report suggest:
·         The market is driven by increasing ratio of late-stage drug failures, resulting in loss of valuable time and investment for drug development. Growth and increasing adoption of OMICS technology is also expected to boost revenue generation in the coming years
·         North America is the largest market for ADME toxicology testing owing to presence of large number of pharmaceutical companies competing for commercial launch of novel molecules
·         Developing regions of Asia Pacific and Latin America are set to grow considerably as many multinational and local players are striving to enter the market. They are also looking improve their hold in markets that present innovation and growth opportunities
·         Some of the key players in this market are Accelrys Inc.; Agilent Technologies, Inc.; Albany Molecular Research Inc.; Beckman Coulter Inc.; Catalent Inc.; Charles River Laboratories International Inc.; AbbVie; Actelion Pharmaceuticals; Amgen; Biocon; BioMarin; Boehringer Ingelheim; Bristol-Myers Squibb; Cipla; and CymaBay Therapeutics.
The global ADME toxicology testing market size was valued at USD 4.33 billion in 2017 and is expected to register a CAGR of 11.4% over the forecast period. A rising number of drug molecules have been failing in the final stages of clinical trials, resulting in loss of valuable time and investments in drug discovery and development. This has resulted in increased investments in the discovery of newer technologies for toxicity testing, which is set to boost the market in the coming decade.
ADME toxicology testing is mainly used for conducting various genetic, chemical, and pharmacological tests that aid the drug discovery process, starting from drug design to drug trails and other drug interactions. This process involves control software, various devices to handle liquids, and other detectors that help rapidly identify active compounds, genetic interactions, and other biomolecular interactions. However, most of these techniques need skilled expertise and software that can handle and store multiple sets of data at a rapid pace. This could limit market growth to an extent.
ADME toxicology testing is now done throughout drug design and development to prevent any late-stage failure and to ensure systematic evaluation to prevent potential loss of a molecule or investment. Most companies follow GLP and non-GLP testing procedures to meet regulatory standards.
Regulatory bodies are being pushed to establish tighter quality control standards to achieve integrity and accuracy of obtained and stored data. However, lack of efficient software to handle automated robotic arms and liquid handling systems is likely to affect the market’s growth.
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https://www.grandviewresearch.com/press-release/global-adme-toxicology-testing-market
Grand View Research has segmented the ADME toxicology testing market by application, technology, method:
ADME Toxicology Testing Technology Outlook (Revenue, USD Billion, 2014 - 2025)
·         Cell Culture
·         High Throughput
·         Molecular Imaging
·         OMICS Technology
ADME Toxicology Testing Application Outlook (Revenue, USD Billion, 2014 - 2025)
·         Systemic Toxicity
·         Renal Toxicity
·         Hepatotoxicity
·         Neurotoxicity
·         Other Toxicities
ADME Toxicology Testing Method Outlook (Revenue, USD Billion, 2014 - 2025)
·         Cellular Assay
·         Biochemical Assay
·         In-Silica
·         Ex-vivo
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.


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