How much will the In-vitro Toxicology Testing industry be worth in the Future????



The global in-vitro toxicology testing market size is anticipated to reach USD 30.9 billion by 2027 and is projected to register a CAGR of 9.2% over the forecast period, according to a new report by Grand View Research, Inc. The new paradigm shift in toxicity testing of animal models toward computational methods such as silico models to interpret toxicity pathway data, drives the demand for in-vitro toxicology testing. These methods provide cost and time efficiency and enhance safety assessment.
Biopharmaceutical innovators are at the forefront of the human response to the coronavirus pandemic. A significant number of major biotech firms are in the midst of a race to investigate the Sars-Cov-2 genome and prepare a viable vaccine for the same. As compared to the speed of response to SARS/MERs etc, the biotech entities are investigating SARs-Cov-2 at an unprecedented rate and a considerable amount of funds are being put into the R&D. With multiple candidates in trial, the public and private sectors are anticipated to work in unison for the foreseeable period, until a vaccine is developed for Covid-19. The report will account for Covid19 as a key market contributor.
Several governments are taking measures to minimize animal-based test models, forming conducive government policies, and providing funds to support in-vitro models. These factors are expected to create ample growth opportunities for the market. For instance, in November 2020, the U.S. National Institute for Environmental Health Sciences planned to provide funds to small companies for the development of engineered 3D culture or organotypic culture models (OCM) in-vitro systems.
Key players operating in the market include Merck KGaA; Charles River; Bio-Rad Laboratories, Inc.; Abbott; Thermo Fisher Scientific Inc.; Catalent, Inc.; GE Healthcare; Quest Diagnostics Incorporated; Eurofins Scientific; Laboratory Corporation of America Holdings; Evotec; Creative Bioarray; Gentronix; BioIVT; SGS SA; and Agilent Technologies.
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https://www.grandviewresearch.com/industry-analysis/in-vitro-toxicology-testing-market/request/rs2
With advancements in high throughput screening, biological screening, and chemical synthesis, the number of publicly available databases containing data related to toxicity; absorption, distribution, metabolism, and excretion (ADME); pharmacovigilance; and drug screening has expanded rapidly. This has enabled scientists to access vast information for toxicity profiling, thereby spurring revenue generation in this market.
Further key findings from the report suggest:
·         Growing application of 3D-spheroid-cultures, particularly for nanoparticle toxicity testing, resulted in the dominance of the cell culture technology segment in 2020
·         Omics technology is anticipated to register lucrative growth as RNA sequencing and shotgun proteomics are increasingly used for a more comprehensive understanding of the effects of toxicants
·         The high usage rate of cellular assays with advancements in cell-based technologies, including label-free detection and high-content screening, has contributed to the dominance of the cellular assays segment in 2020
·         Systemic toxicology emerged as the leading application segment in 2020 as it plays a key role in risk assessment during drug development procedures. For instance, toxicity testing of systemic immunosuppressive drugs and systemic corticosteroids is important during the development of drugs for ocular inflammatory disease
·         Pharmaceutical industry dominated the in-vitro toxicology testing market in 2020 as toxicological testing is a prerequisite step for drug development
·         Stringent government regulations regarding animal usage for toxicity analysis in North America have led to an increased adoption rate of in-vitro models. Hence, North America dominated the global market in 2020
·         The Asia Pacific region is anticipated to witness the fastest growth rate over the forecast period due to increasing initiatives by public agencies to encourage acceptance of non-animal test models
·         Abbott, Thermo Fisher, Agilent Technologies, GE Healthcare, Bio-Rad, and Merck KGaA are some of the key players operating in the market.
The global in-vitro toxicology testing market size was estimated at USD 15.3 billion in 2020 and is expected to register a CAGR of 9.2% over the forecast period. The evolution of 3D cell culture systems that mimic host physiology has enabled safe testing of new compounds in the in-vitro environment, thus limiting the use of animal testing models. This has increased the acceptance of in-vitro toxicology and computational methods, consequently driving the market growth.
Growing ethical concerns regarding animal testing procedures and efforts taken by several animal welfare organizations have paved the way for the replacement or reduction of animal testing with in-vitro toxicology testing. For instance, in April 2018, the U.S. Environmental Protection Agency (EPA) introduced a draft policy which prescribes the use of in-vitro methods to minimize animal use in testing chemicals causing skin inflammation or sensitization.
The broadening horizon of high-throughput screening (HTS) techniques has encouraged drug manufacturers to adopt these cost-effectiveand time-efficient techniques for toxicological evaluation. For instance, in October 2020, the HTS data from the ToxCast program, initiated by the U.S. EPA to evaluate the toxic potential of chemicals, has been utilized for the risk assessment of food contact materials by employing an assessment framework called RISK 21.
In-vitro toxicology assays enable rapid assessment of safety and offer cost-saving as well as time-saving advantages. Drug developers prefer in-vitro toxicology screening of their candidate drugs, further driving the adoption of these assays. Integration of systems biology, toxicogenomics, computational toxicology, and epigenetics in in-vitro methodology also positively impact the adoption rate.
Browse Press Release of this report:
https://www.grandviewresearch.com/press-release/global-in-vitro-toxicology-testing-market
Grand View Research has segmented the global in-vitro toxicology testing market on the basis of technology, method, application, end use, and region:
In-vitro Toxicology Testing Technology Outlook (Revenue, USD Million, 2016 - 2027)
·         Cell Culture Technology
·         High Throughput Technology
·         Molecular Imaging
·         OMICS Technology
In-vitro Toxicology Testing Method Outlook (Revenue, USD Million, 2016 - 2027)
·         Cellular Assay
·         Biochemical Assay
·         In Silico
·         Ex-vivo
In-vitro Toxicology Testing Application Outlook (Revenue, USD Million, 2016 - 2027)
·         Systemic Toxicology
·         Dermal Toxicity
·         Endocrine Disruption
·         Ocular Toxicity
·         Others
In-vitro Toxicology Testing End-use Outlook (Revenue, USD Million, 2016 - 2027)
·         Pharmaceutical Industry
·         Cosmetics & Household Products
·         Diagnostics
·         Chemical Industry
·         Food Industry
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.




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