Pyrogen Testing Market Insights: Rising Production of Pharmaceuticals and Biologics Is Driving Market Growth


The global pyrogen testing market size is expected to reach a value of USD 1.9 billion by 2025, at a CAGR of 13.4% according to a new report by Grand View Research, Inc. Increasing demand for therapeutic drugs including pharmaceuticals, biopharmaceuticals, and biologics is the major factor that propels growth of the market during forecast period. Pyrogen is a toxic molecular substance that causes fever if induced in animal or human body. Pyrogen testing is used by pharmaceutical, biopharmaceuticals, biotechnology, and medical devices companies to confirm the absence of pyrogen. Thus, the companies use various methods such as LAL, in vitro pyrogen, and rabbit test to ensure the quality of products.
Biopharmaceutical innovators are at the forefront of the human response to the coronavirus pandemic. A significant number of major biotech firms are in the midst of a race to investigate the Sars-Cov-2 genome and prepare a viable vaccine for the same. As compared to the speed of response to SARS/MERs etc, the biotech entities are investigating SARs-Cov-2 at an unprecedented rate and a considerable amount of funds are being put into the R&D. With multiple candidates in trial, the public and private sectors are anticipated to work in unison for the foreseeable period, until a vaccine is developed for Covid-19. The report will account for Covid19 as a key market contributor.
Increasing prevalence of chronic diseases, is another foremost factor supporting the market growth. The prevalence of chronic diseases is very high in developed countries and is growing at high pace in developing countries including China and India. Different factors such as unhealthy diet, smoking, alcohol consumption, and lack of exercise leads to occurrence of chronic diseases such as cancer, cardiovascular diseases, diabetes, and chronic respiratory diseases.  Hence, there is a growing demand for therapeutic drugs and medical devices for the treatment of such diseases, which in turn is projected to fuel the demand for pyrogen testing to ensure the quality of products including drugs and devices.
Some of the key players in the market are Merck KGaA; GenScript; Hyglos GmbH; Ellab A/S; Lonza; Thermo Fisher Scientific, Inc.; Charles River Laboratories, Inc.; Associates of Cape Cod, Inc.; and Pyrostar. The major companies are undertaking various strategies initiatives, such as new product development, mergers, acquisitions, collaborations, and regional expansion for serving the unmet needs of their customers.
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Further key findings from the study suggest:
·         Consumables was the largest revenue grossing segment of this market in 2016, owing to the large application of pyrogen testing kits and reagents along with its repetitive purchase
·         Instruments segment accounted for the remarkable share in the market in 2016 and is also expected to showcase significant growth during forecast period, owing to rising demand for pharmaceutical, biologics, and medical devices for treatment and diagnosis
·         The pharmaceutical and biotechnology companies segment dominated the pyrogen testing market in terms of revenue in 2016, due to the large production of therapeutic drugs and growing investment in R&D by companies for drug development
·         North America is the leading regional market and accounted for the largest revenue share in 2016 primarily due to the existence of large number of healthcare companies including pharmaceuticals and medical devices in this region
·         The Asia Pacific region is anticipated to be the fastest growing market during the study period. The growing prevalence rate of chronic diseases in the Asian countries including India and China, is a major factor contributing to the expansion of market in this region.
·         Some major players serving this vertical include Charles River Laboratories, Inc.; Ellab A/S; Merck KGaA; GenScript; Hyglos GmbH; Lonza; Thermo Fisher Scientific, Inc.; Associates of Cape Cod, Inc.; and Pyrostar
The global pyrogen testing market size was valued at over USD 621.8 million in 2016 and is projected to grow at 13.4% over the forecast period. Increasing demand for pyrogen testing products in pharmaceutical and biotechnology industry is a major factor contributing towards the growth of the market. Rapidly growing pharmaceutical and biotechnology industries along with escalating number of new therapeutics launch is expected to boost the demand for pyrogen testing products.
Rising investment in R&D by manufacturing companies and government for new product development is another major factor contributed towards the growth of the market. New product development and launch is a key strategy acquired by manufacturers to maintain their dominance and to get maximum revenue-share in the sector. As stated by European Federation of Pharmaceutical Industries and Associations (EFPIA), in Europe, pharmaceutical industry had invested around USD 43,380 million in R&D in 2014. Thus, the demand for pyrogen testing products is expected upsurge in near future, which is projected to boost market growth.
On the basis of product, the pyrogen testing industry is segmented into consumables, instruments, and services. In 2016, consumables segment was the largest revenue-generating segment and is also estimated to maintain its dominance during the forecast period. Rising prevalence of chronic diseases boosts the production of pharmaceuticals, biologics, and medical devices products. Thus, the increasing production of these products propels the application of pyrogen testing consumables including kits and reagents.
The instruments segment is expected to show lucrative growth during the forecast period owing to the technological advancement in products. For instance, the PyroDetect System is a verified non-animal substitute to replace the rabbit test that offers a high quality in vitro detection of both non-endotoxin and endotoxin contamination. In 2016, instruments segment was followed by services in terms of revenue.
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Grand View Research has segmented the pyrogen testing market on the basis of product, test type, end-use:
Pyrogen Testing Product Outlook (Revenue, USD Million; 2014 - 2025)
·         Consumables
·         Instruments
·         Services
Pyrogen Testing Test Type Outlook (Revenue, USD Million; 2014 - 2025)
·         LAL test
·         Chromogenic test
·         Turbidimetric test
·         Gel clot test
·         In vitro pyrogen test         
·         Rabbit test
Pyrogen Testing End-Use Outlook (Revenue, USD Million; 2014 - 2025)
·         Pharmaceutical and biotechnology companies
·         Medical devices companies
·         Others
About Grand View Research
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.



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